Mizuho OKAMOTO
| Name | Mizuho OKAMOTO |
| Department/Research Field | Redox biology Aging embryo development |
| Research content |
| Coenzyme Q10 (CoQ10) is an essential factor in the mitochondrial electron transport system and also functions as an antioxidant; CoQ10 levels have been shown to change throughout life, but the regulatory mechanisms associated with development and ageing are unknown. I am using cellular and animal models, such as medaka, to elucidate how CoQ10 is regulated in the body. |
 Villalba JM, Navas P. Regulation of coenzyme Q biosynthesis pathway in eukaryotes. Free Radic Biol Med. 2021 Mar;165:312-323.
Schematic diagram of the regulatory mechanism of coenzyme Q10.
Modified from Villalba JM, Navas P. Regulation of the coenzyme Q biosynthesis pathway in eukaryotes Free Radic Biol Med. 2021 Mar;165:312-323.
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| Research theme |
(1) Elucidation of the in vivo regulatory mechanism of coenzyme Q10 (2) Analysis of the coenzyme Q-binding protein prosaposin (3) Elucidation of the role of coenzyme Q in developmental processes. |
| Research keywords |
| Coenzyme Q10 , Aging , embryo development |
| Lab link |